Two field experiments were carried out in the Research Farm at Al-Kawthar, Faculty of Agriculture, Sohag University, in two successive seasons of 2010/2011 and 2011/2012 to study the response of Giza 168 and Sids 12 varieties to three planting methods (Afir broadcast, Afir drill and Afir in furrows) and four weed control trials (hand weeding twice at 30 and 45 days after sowing, Granstar 75% DF at rate 8 g/fed. at 30 days after sowing, Topik 15 % WP at rate of 140 g/fed. at 40 days after sowing and Granstar 75% DF at rate 8 g/fed. at 30 days after sowing + Topik 15% WP at rate of 140 g/fed. at 40 days after sowing) on yield and yield components. A randomize complete block design (RCBD) in split-split plot with four replicates was used. Data indicated that the varieties, planting methods and weed control had significantly effect on the all studied traits; plant height (cm), spike length (cm), number of spikes/m2, number of spikelets/spike, 1000-grain weight (g), grain yield (ardab/fed.) and biological yield (ton/fed.) in both seasons. Sids 12 variety produced the highest number of spikes/m2, number of spikelets/spike, 1000-grain weight, grain yield and biological yield, but Giza 168 surpassed in plant height and spike length. Afir drill method increased significantly number of spikes/m2, number of spikelets/spike, 1000-grain weight, grain yield (ardab/fed.) and biological yield (ton/fed.), as well as Afir broadcast and Afir in furrows methods increased plant height (cm) and Spike length (cm). The application of Granstar 75% DF + Topik 15% WP mixture increased spike length (cm), number of spikes/m2, number of spikelets/spike, 1000-grain weight (g), grain yield (ardab/fed.) and biological yield (ton/fed.). In general the highest grain yield (20.02 ardab/fed.) was obtained from the application of Granstar 75% DF + Topik 15% WP mixture under drill method