Two field experiments were conducted at Agricultural Research Station, East of El-Ewinate, Egypt, during 2013 and 2014 seasons, to investigate the response of some sunflower genotypes to foliar application of some antioxidants under two irrigation levels in East of El-Ewinate conditions. The results could be summarized as follows: - The differences among sunflower genotypes were highly significant for all studied traits except days to 50% flowering and oil % in both seasons. Also, all studied traits except of oil % were significantly affected by water deficit in the both seasons. - The highest mean values of plant height (181.7 and 183.3 cm), stem diameter (1.10 and 1.12 cm), head diameter (27.17 and 24.73 cm), head yield (67.33 and 66.80 g), 100-seed weight (4.49 and 4.59 g), oil yield fed.^-1 (464.95 and 441.56 kg) and seed yield fed.^-1 (1352.0 and 1328.0 kg) were recorded for G₁ (RF₁₅ X A₁₂) genotype irrigated by 100% (I₁) and spray with ascorbic acid (AA) in the first and second seasons, respectively.While the lowest mean values of plant height (133.3 and 131.7 cm), stem diameter (0.713 and 0.710 cm), head diameter (15.47 and 15.20 cm), head yield (28.97 and 32.53 g), 100-seed weight (2.94 and 2.87 g), oil yield fed.^-1 (258.62 and 303.74 kg) and seed yield fed.^-1 (732.0 and 884.0 kg) were recorded for Sakha-53 genotype irrigated by 75% (I₂) and spray with tap water in the first and second season, respectively.