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231613

Mitochondrial Dysfunction and Response After Stressing by Aluminum Nanoparticles (AlNPs) of Helix sp

Article

Last updated: 01 Jan 2025

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-

Tags

Agriculture microbiology

Abstract

The enhanced uses of nanoparticles in our daily life have been augmented according to industrial development. Indeed, the nature and the properties of nanoparticles make them a good choice in many products from food enhancers, drugs, nanomaterials, medicine, electronics and cosmetics.  
Our study is a trial on the effects of AlNPs (<10nm) on the mitochondrial status and possible dysfunction in detoxication organ of the snail Helix sp < em>. and to assess the impact of these nanomaterials on swelling, permeability and respiration of hepatopancreatic mitochondria.
Obtained results presents an increased activity of many mitochondrial metabolization enzymes (mitGST, mitCAT, mitMDA, mitGPx) and a decrease in GSH level. Thus, an increase in mitochondrial swelling and permeability have been showed with a slow rate of respiration level according to the controls group.
Finally, our results suggested that nanoparticles of aluminum affect directly the mitochondrial function by the perturbation of general metabolic status of snails exposed to 5 and 10μg /g of NPs of Al each 2 days.
 

DOI

10.21608/asejaiqjsae.2022.231613

Keywords

AlNPs, Helix sp, mitCAT, mitGPx, mitGST, swelling, Respiration, Permeability

Authors

First Name

Tahar

Last Name

Goudjil

MiddleName

-

Affiliation

Laboratory of toxicology and ecosystems pathologies, Applied Biology department, Larbi Tebessi University, 12000, Tebessa, Algeria.

Email

-

City

-

Orcid

-

First Name

Sarra

Last Name

Zouaoui

MiddleName

-

Affiliation

Laboratory of toxicology and ecosystems pathologies, Applied Biology department, Larbi Tebessi University, 12000, Tebessa, Algeria.

Email

-

City

-

Orcid

-

First Name

Souhaila

Last Name

Bekkairi

MiddleName

-

Affiliation

Laboratory of toxicology and ecosystems pathologies, Applied Biology department, Larbi Tebessi University, 12000, Tebessa, Algeria.

Email

-

City

-

Orcid

-

First Name

Salim

Last Name

Gasmi

MiddleName

-

Affiliation

Laboratory of toxicology and ecosystems pathologies, Applied Biology department, Larbi Tebessi University, 12000, Tebessa, Algeria.

Email

-

City

-

Orcid

-

First Name

Fouad

Last Name

Menaceur

MiddleName

-

Affiliation

Laboratory of toxicology and ecosystems pathologies, Applied Biology department, Larbi Tebessi University, 12000, Tebessa, Algeria.

Email

-

City

-

Orcid

-

First Name

Rachid

Last Name

Rouabhi

MiddleName

-

Affiliation

Applied biology department, tebessa university, Algeria

Email

r_rouabhi@univ-tebessa.dz

City

TEBESSA

Orcid

0000-0001-6809-636

Volume

43

Article Issue

2

Related Issue

32901

Issue Date

2022-04-01

Receive Date

2022-03-10

Publish Date

2022-04-01

Page Start

211

Page End

218

Print ISSN

1110-0176

Online ISSN

2536-9784

Article File

ASEJAIQJSAE_Volume 43_Issue 2_Pages 211-218.pdf

PDF . 331.9kB

Link

https://asejaiqjsae.journals.ekb.eg/article_231613.html

Detail API

https://asejaiqjsae.journals.ekb.eg/service?article_code=231613

Order

4

Type

Original Article

Type Code

53

Publication Type

Journal

Publication Title

Alexandria Science Exchange Journal

Publication Link

https://asejaiqjsae.journals.ekb.eg/

MainTitle

Mitochondrial Dysfunction and Response After Stressing by Aluminum Nanoparticles (AlNPs) of Helix sp

Details

Type

Article

Created At

22 Jan 2023