Beta
ManageSearchChatDiscover
177465

Quinoa Mitigates Chlorfenapyr-Induced Testicular Toxicity in Rats

Article

Last updated: 01 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Plant pest management

Abstract

Chlorfenapyr (Chf), belongs to a new chemical class calledhalogenated pyrroles, used extensively in Egypt. Negative effects of pesticides on the male reproductive system have been shown broadly. In recent years, the use of medicinal herbs in reducing pesticide toxicity has increased worldwide; one of these herbals is Quinoa seeds (QS), contains high amount of protein, vitamins, and minerals. Our study evaluated the effects of QS on testicular toxicity in rats exposed to Chf. Twenty rats were divided into four groups; group (I) as control was fed on basal diet only, group (II) QS at 30% from the basal diet, group (III) 180 mg/kg b.w/day of Chf, was fed on basal diet only and group (IV) Chf at 180 mg/kg b.w/day plus QS at 30% from the basal diet, the experimental period was four weeks. Rats were sacrificed and blood serum, sperm, and sexual organs samples were collected for biochemical and histomorphological studies. Results revealed that Chf treated animals showed sagging testicles with increased the testis relative weights. This effect was associated with a decline in count, motility, and viability of sperms, and increased sperm abnormality, and a decrease in sex hormones level (P<0.05). On the other hand, QS showed improvement in almost all estimated parameters and mitigated all the toxic effects of Chf, which was confirmed with the histological examination of the testis. So, we can encourage QS consumption as a clue for the toxicity and infertility problems revealed as a result of chlorfenapyr exposure.       
 

DOI

10.21608/asejaiqjsae.2021.177465

Keywords

chlorfenapyr, testicular toxicity, Rats, Quinoa

Authors

First Name

Nadia

Last Name

Hamed

MiddleName

Ali

Affiliation

Researcher Dept. of Mammalian and Aquatic Toxicology, Central Agricultural Pesticides Laboratory (CAPL), Agricultural Research Center (ARC), Alexandria, Egypt nadia010560@gmail.com 01005603031

Email

nadia010560@gmail.com

City

الاسکندرية

Orcid

-

Volume

42

Article Issue

2

Related Issue

23719

Issue Date

2021-04-01

Receive Date

2021-04-30

Publish Date

2021-06-30

Page Start

475

Page End

486

Print ISSN

1110-0176

Online ISSN

2536-9784

Article File

ASEJAIQJSAE_Volume 42_Issue 2_Pages 475-486.pdf

PDF . 1.0MB

Link

https://asejaiqjsae.journals.ekb.eg/article_177465.html

Detail API

https://asejaiqjsae.journals.ekb.eg/service?article_code=177465

Order

21

Type

Original Article

Type Code

53

Publication Type

Journal

Publication Title

Alexandria Science Exchange Journal

Publication Link

https://asejaiqjsae.journals.ekb.eg/

MainTitle

Quinoa Mitigates Chlorfenapyr-Induced Testicular Toxicity in Rats

Details

Type

Article

Created At

22 Jan 2023