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106475

Effective Dose of Vitamin C Against Passive Smoking

Article

Last updated: 01 Jan 2025

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Subjects

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Tags

Home economics

Abstract

Objective: Ascorbic acid (AA), known as vitamin C, plays an important role in the human body. Therefore, this study aimed to estimate the beneficial effects of two levels of (AA) that can protect or cure the lung against the hazards of passive smoking in male mice.
Materials and Methods: The study was done on forty male albino mice (6 weeks age and average body weight 22 ± 3 g). The mice were assigned into eight equal groups; control group, group 2was exposed to cigarette smoke for 12 weeks, and the other six groups were given low or high doses of vitamin C(0.015and 0.075 mg/g BW)before, during and after exposure to smoke. Doses were given orally via oro-gastric tube.
Results: High doses of vitamin C had a protective effect when taken before and during exposure to smoke. It reduced the negative effect of smoke as indicated by the levels of TBARS and GSH in plasma and lung tissue, and the improvement of studied histological parameters.
Conclusion: Ascorbic acid had no therapeutic effects after lung tissue damage due to exposure to secondhand smoke.Therefore, it is important to protect the lung from the negative effects of smoking by increasing the daily intake of vitamin C doses to 1 gram, from food rich in vitamin C like fresh fruits and vegetables.
 

DOI

10.21608/asejaiqjsae.2020.106475

Keywords

vitamin c, passive smoking, lung, biochemical, Histological examinations

Authors

First Name

Soheir F.

Last Name

Nour

MiddleName

-

Affiliation

Department of Home Economics, Faculty of Agriculture, Alexandria University (Egypt.)

Email

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City

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Orcid

-

First Name

Tayseer M.

Last Name

El-Assar

MiddleName

-

Affiliation

Agriculture Research Center(Egypt.) .

Email

-

City

-

Orcid

-

First Name

Noha M.

Last Name

Zahran

MiddleName

-

Affiliation

Histology Department, Faculty of Medicine, Alexandria University (Egypt.).

Email

-

City

-

Orcid

-

Volume

41

Article Issue

APRIL-JUNE

Related Issue

13087

Issue Date

2020-06-01

Receive Date

2020-04-02

Publish Date

2020-06-30

Page Start

295

Page End

304

Print ISSN

1110-0176

Online ISSN

2536-9784

Article File

ASEJAIQJSAE_Volume 41_Issue APRIL-JUNE_Pages 295-304.pdf

PDF . 822.3kB

Link

https://asejaiqjsae.journals.ekb.eg/article_106475.html

Detail API

https://asejaiqjsae.journals.ekb.eg/service?article_code=106475

Order

13

Type

Original Article

Type Code

53

Publication Type

Journal

Publication Title

Alexandria Science Exchange Journal

Publication Link

https://asejaiqjsae.journals.ekb.eg/

MainTitle

Effective Dose of Vitamin C Against Passive Smoking

Details

Type

Article

Created At

22 Jan 2023