Two field experiments were carried out in EL-Wasiata district (EL-Jabal EL-Akhdar) during summer seasons of 2015 and 2016 to study drought effect for ten days during heading stage of maize (Zea mays L.) on yield and its attributes and grain oil and protein content of ten maize genotypes. Split-plot with four replication was used, where the two drought treatments were distributed as whole plot, while the ten genotypes were randomly allocated in sub plot. Obtained results revealed that the irrigation (non-stressed) treatment was significantly superior than drought (stressed) treatment for all the studied traits, except ear diameter in the two seasons. Single crosses, especially Sc128 and Sc168 were superior than Triple crosses and open pollinated varieties for all the studied traits in the two studied seasons, except number of rows/ ear in the second season and ear diameter in both seasons, where the open pollinated varieties had the thickest ears. Regarding the interaction between the two factors, results indicated that SC 128 and SC 168 under (non-stressed) treatment had the highest number of grains/ row in both seasons, while the heaviest 100-grain weight resulted from SC128 and SC30K8 in the first and second seasons, respectively, under non-stressed conditions. Also, SC 128 in the two seasons and SC 168 in the second season showed the highest grain yield under (non-stressed) condition.