The present work aims at investigating the capability of Hibiscus and green tea extracts in reducing or decreasing the DHA damage induced by the drug indexan as a well known positive control. Human lymphocyte genome was chosen and employed to achieve such a purpose. Two genotoxic bioassays were employed .they are: 1- In vitro induction of SCE Sister chromatid exchange2- Chromosomal aberrations the obtained results, clearly showed that both extracts was proven to be capable in decreasing or reducing micro as well as macro DNA damage. This results, however, presented that the tested extracts are positive as anticlastogonic agents.