Based on the growing interest in disability issues and serious effects on all levels, The present study aimed mainly to revealing the nature of the relationship between the performance of awareness of family responsibilities among mothers of children with cerebral palsy and life satisfaction, Where data were met through the application of research tools of (general data form, awareness of the performance of family responsibilities scale, a measure of satisfaction with life) on a predetermined sample consisted of (100) mother from attending their children with cerebral palsy on a regular basis on the Neurosurgery Clinic in Mansoura University Children's Hospital,selected from different social and economic levels, The research has come to the set of results was the most important Including; There were significant differences between the mean sample in awareness of the performance of family responsibilities degrees (towards the disabled son) in favor of the least degree of disability, and (toward the disabled son- economic responsibilities) in favor of accommodation in cities, as well as the presence of statistically significant differences between the averages of the research sample in personal life satisfaction In favor of the least degree of disability,  While there were no statistically significant differences between the mean scores of the research sample in each of awareness of the performance of family responsibilities and life satisfaction (dimensions - the total score) according to the sex of the child with a disability, The results also resulted in the presence of statistically significant differences between the mean statistical sample in awareness of the performance of family responsibilities degrees (towards the disabled son) In favor of the Sorted AD younger disabled child, as well as in the performance of awareness of family responsibilities (the total score) in favor of the largest age group of the mother, the highest educational level of parents and The least number of family members, In addition to the presence of statistically significant differences between the mean statistical sample in life satisfaction score in favor of each of the older age group,highest level of education of the mother top and hightest monthly income of the family, and the existence of a positive correlation between the performance of each of awareness of family responsibilities (towards the disabled son toward Family members - the total score) as well as family life satisfaction and total score, While there were no correlation between awareness of the performance of family responsibilities (toward home-economic responsibilities), and satisfaction with personal life. The researcher submitted number of recommendations that describes some of the strategies that serve pregnant mother and child with a disability and his family, And improve the level of quality of care and services provided by the Ministry of Health, medical centers, hospitals and specialized agencies .