The present study was designed to estimate the effect of mineral fertilizer NPK (19:19:19) at 0.0, 5.0, 10.0 and 15.0 g / plant, bio-fertilizer (active dry yeast) at levels 0.0, 2.0, 4.0, and 6.0 g/ l and their combination on growth, flowering and leaves chemical composition of Anthurium andreanum, L. plants. The experiment was carried out during 2010 and 2011 growing seasons in Alexandria university's nursery. The results indicated that planting Anthurium andreanum, L. under greenhouse  conditions with applying 10 g / pot  of mineral NPK monthly during the growing seasons, combined with active dry yeast at 6 g / l improved the vegetative growth and flowering parameters ( plant height, number of leaves, leaf area, leaf dry weight, number of flowers / plant, flower dry weight and leaf chemical composition parameters [ total chlorophyll and mineral content (N, P and K %)]. These results can be used for improving Anthurium fertilizing programs for economic production.