The two  predatory mites, Phytoseiulus persimilis Athias-Henriot and Neoseiulis californicus (McGregor) were used against the two-spotted spider mite, Tetranychus urticae Koch as well as the bio-pesticide product (Romachtin) on four pepper cultivars; two of which with red fruits ('Lorekii' and 'Depika') and the others with yellow fruits ('Liobii' and 'Cobly').  The two  yellow cultivars (especially Llobii) were less  susceptible to  mite infestation  than  the  two  red cultivars. The used biological control agents reduced populations of all T urticae stages on the aforementioned pepper cultivars. These reduction percentages revealed that, N. californicus gave the highest on the three pepper cultivars ('Lorekii', 'Depika'  and 'Cobly'), while for the fourth cultivar, good results were obtained by both Romachtin or P.persimilis.