The aim of this research was to evaluate the effect of three sugarcane waste by-products (pressmud PM, bagasse ash BA and molasse MO) which used as soil amendments of for immobilizing some heavy metals such as Cd, Cu, Cr, Ni and Pb in a contaminated soil near industrial factors of Qena Governorate, Egypt. The applied wastes at three levels of 0, 2.5 and 5 % (w/w) were incubated into the contaminated soil for a period of 120 days with wetting and drying cycles. The soil pH, organic matter content and DTPA extractable metals were determined after 30, 60 and 120 days of the incubation periods. The results indicated that BA addition to the contaminated soil have a high effective on reduce the soil content from DTPA-extractable of Cu, Ni and Pb compared with other treatments. Molasse (MO) application caused the best reduction in the mobility of Cd and Cr than BA and PM, while the application of pressmud (PM) had a moderate effect in reducing Ni and Pb of the soil.