Lufenuron (chitin synthesis inhibitors) and Oryza sativa bran extract (waste product) exhibited insecticidal activity on females of Schistocerca gregaria when they were treated as one day old of the 5^th nymphal instar with different concentrations of tested compounds. Some biological aspects, failure of ecdysis to adults, adult mortality, prolongation in the age of last nymphs and developmental events were investigated after treatment.
         Quantitative and qualitative determination of protein and DNA contents were investigated in normal and affected eggs which resulted from females Schistocerca   gregaria treated as one day old 5^th nymphal instarwith LC₅₀ ofLufenuron and Oryza sativa bran extract during embryogenesis. The total protein content of normal eggs at 0-day old, was 81.07 mg protein/gm eggs, after one day of oviposition  the total protein increase significantly (p<0.05). Then the protein content, during the early incubation period, to the 4^th day post oviposition (pop) significantly (p<0.05) declined sharply to 38.74mg protein / gm eggs. While in the 7^th, 11^th &12^th it was decreased significantly (p<0.05) during the late organogenesis stage. The treatment resulted a significant decrease in the total protein of rice bran extract affected eggs compared with the control at (1, 11& 12) days old eggs, and a significant increase at 0 and 4 days pop compared with control. Treatment with Lufenuron resulted a significant decrease of total protein in (0, 1 & 12) days old eggs compared with the control but there were no significant increase at 4, 7 and 11 old eggs. A total of (10 -12) protein bands were separated by electrophoresis during normal embryogenesis of Schistocerca   gregaria. Fraction protein of affectedeggs with LC₅₀ of Lufenuron and rice bran extract resulted a separation of (10 – 14) and (11- 14) protein bands with molecular weights from 12 to 325 KDa. Data recorded significant differences between DNA content of normal and the affected Schistocerca gregaria eggs throughout embryogenesis (0-12 days) post-oviposition