The experimental data indicated that, regardless the effect the planted crop, Baicao2 (Matrine) and Neemix (Azadirachtin) were more toxic alternative pesticides against (Coccinella undecimpunctata aegyptiaca Reihe and Coccinella septempunctata L.). The average reduction percentages were 99.17 and 94.06% and 100.00 and 96.38% with general mean (99.58 and 95.72%) during the two planting seasons, respectively. The results indicate that, Biosect (Beauveria bassiana) compound was the most harmful alternative pesticide against the true spiders. This compound induced (70.19 and 72.94%) as an average reduction percentage during the early summer and Nili plantation, respectively. The lower toxic effect was obtained with the treatment by Prev (orange oil) where, the general mean reduction percentage after two seasons of application was 14.63%. Baicao and Neemix showed a moderate toxic effect on the population density of the true spiders.