Monitoring of organophosphorus and heavy metals was carried out in Abd El-Aal Canal, Kerdasa agricultural area, Cairogovernorate to investigate the level of pollution with these contaminants in the aquatic ecosystems feeding farms. Samples were collected from Abd El-Aal Canal and analyzed by ICP-AES to detect cadmium, copper, iron, manganese, lead and zinc, and analyzed by GC to detect organophosphorus pesticides. Results revealed that the highest detected concentrations of manganese were (0.108 ±0.008 mg/L) and lead (0.18 ±0.002 mg/L) both were found exceeding the standard accepted limits. Only chlorpyrifos insecticide was detected in tested samples, and it was above the standard limits as well. As a result, the increased levels of chlorpyrifos, manganese and lead in Abd El-Aal Canal may cause stress to the aquatic ecosystem. The high level of detected contamination indicates potential danger on aquatic animals, farm animals, agricultural crops, and eventually human health. simple and economical methodology to remove pollutants from aquatic systems is recom-mended.