Beta
42579

Multifocal electroretinogram and multifocal visual evoked potential studies as early detectors of diabetic retinopathy in type I diabetes mellitus

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Neurophysiology

Advisors

El-Khouli, Sali , El-Senbari, Zainab , Nada, Muna A. , El-Fayyoumi, Nivin M.

Authors

Salem, Elham Nabil Fayed

Accessioned

2017-07-12 06:41:19

Available

2017-07-12 06:41:19

type

M.D. Thesis

Abstract

Aim: to detect preclinical stage of diabetic retinopathy in type I Diabetic children using the mfERG and mfVEP tests.Method: 60 eyes of 30 diabetic child and 40 eyes of matched age and sex 20 healthy children were examined and confirmed with no diabetic retinopathy by ophthalmological examinations and flouroscein angiography. The diabetic patients with at least 10 years duration type I DM.mfERG and mfVEP were recorded using the RETi scan system (Roland consult,Wiesbaden ,Germany). Quadrants analysis of the amplitude and implicit time of P1 wave of the mfERG and also quadrant analysis of the amplitude and implicit time of P wave in mfVEP were used to compare between patient groups and controls.Result: The P1wave amplitude showed statistically significant reduction in all quadrants in both mfERG and mfVEP tests, with no statistical significant difference concerning the peak time except in the lower temporal and lower nasal quadrants in mfVEP tests. The results were statistically correlated with the duration, age and HbA1c level. Conclusion: The mfERG and mfVEP reduction in amplitude may be used as a predictor for the development of diabetic retinopathy in the inner layers of the retina in subclinical cases.

Issued

1 Jan 2014

DOI

http://dx.doi.org/10.21473/iknito-space/36516

Details

Type

Thesis

Created At

05 Feb 2023