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The epididymis and its antioxidant activityin seminal plasma

Thesis

Last updated: 06 Feb 2023

Subjects

-

Tags

Dermatology, Andrology & STDs

Advisors

Mouemen, Muhammad N., El-Nashar, Abdel-Rahman M., Muhammad, Hager E.

Authors

Barsoum, Nader George

Accessioned

2017-03-30 06:22:43

Available

2017-03-30 06:22:43

type

M.Sc. Thesis

Abstract

To assess the contribution of the epdidiymis to seminal plasma antioxidant activity by comparing the semen of normozoospermic and obstructive azoospermic individualsMethods: Semen samples were obtained from men presenting for infertility assessment, normozoospermic (n=30) and obstructive azoospermic men (n=30). Total seminal plasma antioxidant activity was measured, as were concentrations of urate, ascorbate and thiols, antioxidants that are abundant in human semen. Malondialdehyde (MDA) concentration was measured to indicate lipid peroxidation.Results: Total antioxidant activity and thiol content were significantly lower (P<0.001) in the plasma from obstructive azoospermic men compared with that of normozoospermic donors. Ascorbate and urate were found at similar concentrations in the plasma of both groups. The concentration of MDA was significantly higher (P <0.001) in the semen from obstructive azoospermic individuals compared with the normozoospermic group.Conclusions: The results indicate that the epididymis contributes to the antioxidant capacity of seminal plasma and possesses region-specific antioxidant activity.

Issued

1 Jan 2002

Details

Type

Thesis

Created At

05 Feb 2023