The study was done among 100 cases admitted in GE Unit, Children's hospitals, Cairo University. It was done on fifty cases receiving racecadotril (Group A) and another fifty cases as a control group (Group B). It was revealed that the mean weight of stool in the 2nd day was 155.76 g with standard deviation of 37.174 in group A, while in group B it was 226.40g with a standard deviation of 29.881. The mean weight of stool in the 3rd day was 91.10 g with standard deviation of 21.863 in group A, while in group B it was 229.38g with a standard deviation of 33.340. It also revealed that the mean weight of patient in the 2nd day was 9.682kg with standard deviation of 3.050 in group A, while in group B it was 10.694kg with a standard deviation of 1.524. The study shows that racecadotril reduces significantly the volume and weight of stool, and protects the patient from weight loss due to dehydration. This study revealed that racecatodril showed improvement and correction of mild acidosis.