Alzheimer's disease is now the most common cause of dementia.Increased oxidative stress, accumulation of oxidatively damaged nucleicacids, proteins, and lipids and inflammation induce deficits in cognitiveand psychomotor performance and play an important role in developmentof Alzheimer's disease (AD). AD was induced in rats by giving AlCl3 (17mg / kg b.wt). Aqueous infusions of ginger (Zingiber officinale) (108 and216 mg / kg b.wt), Boswellia serrata (45 and 90 mg / kg b.wt),rivastigmine (0.3 mg / kg b.wt) were given orally to study their protectiveas well as therapeutic effects on AlCl3 induced AD in rats, which wereevaluated by using behaviour stress tests as activity cage, rotarod and Tmazeas well as by biochemical tests for detection of ACh and ACh E inbrain homogenate and histopathologic examination.Ginger and Boswellia serrata produced protective and therapeutic effectson AD.