Objective: To establish whether uterine artery resistance index (RI), Pulsatility index (PI) and systolic over diastolic ratio (S/D) in healthy pregnant women in early second-trimester has a relation with birth weight.Methods: This was a cross-sectional study of 32 pregnant women attending routine ultrasound examination at 16 – 22 weeks’ gestation. Uterine artery RI, PI and S/D were measured. Birth weight and customized centiles, calculated by centile calculator version 5.12.1 of birth weights were plotted against Doppler value using Pearson product-moment correlation coefficient.Results: The Pearson product-moment correlation coefficients in evaluating the Pulsatility Indices (PI), Resistance Indices (RI) and Systolic flow over diastolic flow ration (S/D) were , 0.05, -0.07 and 0.02 for absolute weights and -0,21, -0.09 and -0.06 for customized percentiles respectively.Conclusion: A non significant correlation exists between birth weight, customized percentiles and first-trimester uterine artery Doppler parameters.