Patients and methods: This study recruited 1576 patients scheduled for CABG, divided into two main groups. The group A includes 500 patients. Mean age was 60.78 ± 6.09 ranging between 45 and 77 years, 415 were males (83%) and 85 were females (17%). This group had data about age, sex, risk factors for atherosclerosis (smoking, HTN, DM, dyslipidemia and +ve family history of CAD) and associated diseases mainly (TIAs, CVS,PVD and renal dysfunction). The data includes also mode of presentation, echocardiographic assessment of L.V. systolic function, the detailed coronary angiographic data as well as the duplex parameters of the carotid and radial arteries as well as GSV. The group B includes 1076 patients, 964 males (89.6%) and 112 females (10.4%). Mean age was 57.05 ± 9.2 ranging between 24 and 83 years. This group had data about only age, sex and duplex parameters of the carotid& radial arteries as well as the GSV. All patients were classified into three subgroups according to carotid duplex data: subgroup 1: those have carotid stenosis ≥ 70% in either side,subgroup 2: those have carotid artery stenosis insignificant (< 70%) and subgroup 3: those with normal carotid artery i.e. no plaques and IMT is ≤1mm in both sides).Results: Severe carotid artery stenosis (≥ 70%) was detected in 37 patients(2.3%) of the whole patients and in the group A they were 13 patients(2.6%). Predictors of severe carotid artery stenosis were significant LM lesion, TIAs, smoking, HTN and male gender respectively.There were 388 patients (24.6%) with radial artery not suitable as a bypass graft; 277 of them (17.6%) has small diameter <2mm and 111 patients (7%)had radial dependent blood supply of their hands.There were 2463 examined lower limb having diameter between 2-5 mm in the mid-thigh (78%) and 2254 limbs having the same diameter range in midleg (71.5%). Pathological abnormalities in GSV were varicose veins (0.4%),post phlibitic limb (1.2%) and acute DVT (0.2%).Conclusion: Severe carotid artery stenosis was detected in 2.3% of patients with multi-vessel CAD. Radial artery wasn’t suitable as a bypass graft in(24.6%). Pre-operative GSV duplex was of great value in identifying the exact anatomic and pathological data about the vein.