The effect of vitamin A administration on the taste buds of old rabbits will be examined using the transmission electron microscope. The study carried out on 20 old aged rabbits divided into two equal groups for the control and the experimental ones. Animals of the experimental groups were administrated vitamin A orally mixed with food for 2 months (2700 IU/kg food). Histological results: Control group the number of taste buds ranges from 4 to 8 per papilla. The taste buds were not equally distributed on the inner and the outer wall of the circumvallate trough through this experiment. The taste pores could not be detected as the cutting section may not pass through it. Experimental groups: There was an apparent increase in the number of taste buds per papilla in comparison to the corresponding control groups after vitamin A administration. It showed enhancement in the numbers of the tasted buds following vitamin A administration which declined in the corresponding control groups. Also reappearance of the taste pores in most of the taste buds detected. Electron microscopic results: Cells type I, II and III could be distinguished and the basal cells could be observed in some sections. Large numbers of nerve fibers were observed. The intergemmal spaces between the taste bud cells were noted. Several synapse-like specializations observed between taste bud cells and the apposed nerve fibers. Control group: The control group showed increased number of myelin figures in the connective tissue which is one of the aging signs. Experimental group: cells type I showed apoptosis. Intermediate filaments observed in the cytoplasm of cells type I, II and III surrounding the nucleus or dispersed in the cytoplasm. Absence of myelin figures in the connective tissue observed. From this experiment it was concluded that: The variation in the appearance of the cell types (I, II and III) may suggest a progressive metamorphosis of these cells. Vitamin A enhances and keeps the gustatory system functioning in the old age.