Background: Critical care nurses are direct care providers for patients in the intensive care unit, particularly oral care. An oral care bundle has been depicted to lower ventilator-associated pneumonia and maintain oral health. Nurses' practice of oral care is not consistent, highlighting the need to receive training and education to narrow the gap between evidence and practice and improve patient outcomes. Aim: The aim of this study was to investigate the effect of oral care bundle educational sessions on critical care nurses' practice. Method: Using a quasi-experimental research design, we assessed the practice of a convenience sample of 41 critical care nurses from a university-based hospital in Egypt pre- and post-educational sessions. Data were collected using the nurses' practice of oral care bundle tool. Results: The overall nurses' practice of oral care bundle interventions was significantly improved post-educational sessions than pre-educational sessions (p< 0.001). Conclusion and Recommendations: The oral care bundle educational sessions can improve overall nursing practice. Therefore, nurses need to continue learning and incorporate recent evidence into their practice.