Background: Foreign body aspiration is a serious emergency in children, potentially leading to complications such as pneumonia, atelectasis, and choking. Educating mothers about the prevention and management of choking is crucial for reducing its associated morbidity and mortality. Aim: The aim of the study was to evaluate the effect of role-play training on mothers' knowledge, practices, and self-confidence in preventing their children from choking and foreign body aspiration. Design: The present study used a quasi-experimental research design. Subjects: A convenient sample of 125 mothers with their children. Setting: The study was conducted at the paediatric outpatient clinics in Suez Canal University Hospitals. Tools: Three tools were used: Tool I: A structured questionnaire on foreign body aspiration and choking. Tool II: An observational checklist for paediatric foreign body airway obstruction. Tool III: A self-confidence assessment scale. Results: The overall mean scores of mothers' knowledge and practices were higher immediately after role play training than before, with significant statistical differences, besides improvement in mothers' self-confidence levels in handling choking emergencies in children before and after training. Conclusion: Mothers' training through role-play regarding choking management from foreign body aspiration in their children significantly improved their knowledge, practices, and self-confidence levels. Recommendations: Continuous training of mothers using a non-traditional educational method such as role play regarding management of foreign body aspirations and choking in children is needed.