Background: Prostate cancer (PC) is the commonest cause of cancer-related death in men globally. So, patients need accessible and adequate health education regarding preventive and diagnostic strategies to appraise their knowledge, practice and perception as an outcome. Aim: To evaluate the effect of prostatic cancer educational program on patients' health outcomes. Method: A quasi-experimental design was used to complete the study on 60 patients as a purposive sample chosen by simple random sampling technique. Tools: I) Structured interview questionnaire including patients' personal data, Clinical data, and knowledge, II) Prostatic cancer preventive practices questionnaire (PCPPQ), III) Prostatic cancer perception questionnaire. Setting: The study was carried out in the urology departments at Suez-Canal and Ain shams University Hospitals, Egypt. Results: here is a statistically significant difference related to knowledge practices, and perception levels of the studied patients regarding prostate cancer pre-, immediate post and post-one month of implementing the educational program. Conclusion: The educational program has significant effect on improving patients' with PC outcomes.  Recommendations: Identify and address common barriers to prostate cancer screening, such as financial issues, lack of health insurance misconception.