Background: The experience of a burn injury can be a substrate for the development of negative impacts on an individual's biopsychosocial well-being. Post-burn training programs are       crucial for patients' optimal health quality, aiming to facilitate a faster return to daily activities and work. Aim: This study aimed to evaluate the effect of training program on quality of life (QoL) and post-traumatic symptoms (PTSS) among patients with burns. Design: Quasi-experimental research (one group pre-posttest). Setting: The study was implemented at the outpatient clinics of the burn unit at El-Demerdash University Hospital. Subjects: 50 patients with burn who were selected purposively. Tools: A structured interviewing questionnaire (socio-demographic characteristics and clinical data tools, Burn-Specific Health Scale-Brief (BSHS-B), and Impact of Event Scale-Revised (IES-R)). Results: This study revealed a positive improvement in QoL and a reduction in experiencing PTSS among the studied patients after the program implementation. There was also a high negative correlation between total QoL and total PTSS among the studied patients in post- program implementation. Conclusion: Post-burn training program positively enhanced the QoL and reduced the PTSS of the studied patients. Recommendations: Educational and counseling programs should be conducted for patients and their families regarding burn management based on their needs.