Background: Parental satisfaction with nursing care reflects the completion of patients' needs and expectations, which are important for health outcomes and hospital quality management. Aim: To assess parents' satisfaction related to the nursing care provided to their children at Pediatric Intensive Care Unit and ward. Design: Descriptive research design. Setting: Pediatric Intensive Care Unit and pediatric ward at Sohag University Hospital. Sampling: Convenience sampling of children's parents meet inclusion criteria (340 parents). Tools: two tools for data collection were used as following: Tool (1) Interview questionnaire had: Demographic data of parent and children and Clinical data of children. Tool (2) “EMPHATIC" questionnaire. Results: The majority of the studied parents (71.8%) had neutral satisfaction level. There was statistically significant relation between the total studied parents' satisfaction and their age, level of education. Conclusions: The parents' satisfaction level related to care was neutral in addition to age of parents, their sex, nature of work, place of residence and education, the age of the child, their diagnosis and duration of hospitalization are determinants of parental satisfaction with nursing care. Recommendations: implementing a periodic assessment of parent satisfaction with care in ward and PICU to increase parents' satisfaction with care.