This paper examines the factors influencing high school students' enrollment intention in National Universities. A conceptual model was constructed and tested using a quantitative research technique. The data was collected using an online questionnaire from 230 high school students in Egypt aware of the National Universities and analyzed using SPSS software. This research's findings proved a positive weak relationship between Student-related factors and students' enrollment intention in National Universities. It was also found that there is a positive moderate relationship between University-related factors and students' enrollment intention in Egyptian National Universities. There is a positive relationship between Student Social Surroundings factors and students' enrollment intention in National Universities. Accordingly, various recommendations are proposed by the authors for the policymakers and the managers of National Universities to increase their efforts in spreading awareness about this new type of university.