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332134

Parkinson's disease and thyroid dysfunction: Effects on severity and risk of cognitive impairment Abeer A.Tony1, Emad F Kholef,2 Effat AE.Tony3, Kerollos N Helmy4, Ahmed Shoeb5

Article

Last updated: 29 Dec 2024

Subjects

-

Tags

Neurology and Psychiatry

Abstract

Background: A serious public health issue, Parkinson's disease is a neurological condition. There aren't many researchs that explain the link between Parkinson's disease and thyroid problems. Objective: This study's objective was to assess thyroid function in people with Parkinson's disease and explain how it relates to the degree and likelihood of cognitive impairment. This study's design was cross-sectional. Methods: From June 2021 to July 2022, our University Hospitals recruited 40 Parkinson's disease patients who had been diagnosed consecutively using the UK Parkinson's Disease Society Brain Bank Diagnostic Criteria. A complete neurological examination and detailed history collection were performed on the patients in order to estimate the severity of their Parkinson's disease. Their mental capacity was tested. Antithyroid antibodies and thyroid hormone serum levels were measured. Results: According to our investigation, all thyroid measures were within normal bounds. We
Conclusion: Despite the fact that hypothyroidism was not more prevalent in our patients with Parkinson's disease, we believe that individuals exhibiting deteriorating symptoms that cannot be attributed to disease progression or resistance to medication modification should have their thyroid function checked. Future research is required to determine whether L-thyroxine hormone therapy improves cognitive function in Parkinson's disease patients.

DOI

10.21608/aumj.2023.243639.1085

Keywords

UK Parkinson's Disease Society Brain Bank Diagnostic Criteria, thyroid hormones, Antithyroid Antibodies, and Cognitive Functions

Authors

First Name

Abeer

Last Name

Toni

MiddleName

-

Affiliation

Assistant Professor of Neurology , Department of Neuropsychiatry, Faculty of Medicine, Aswan University, Egypt

Email

abeer.tony@aswu.edu.eg

City

Aswan

Orcid

-

First Name

Emad

Last Name

Mohammed

MiddleName

Farah

Affiliation

Assistant Professor of clinical pathology, Department of clinical pathology, Faculty of Medicine , Aswan University , Egypt

Email

efm_kholef@yahoo.com

City

Aswan

Orcid

-

First Name

Effat

Last Name

Toni

MiddleName

-

Affiliation

Professor of Neurology, Department of Internal medicine, Faculty of Medicine, Assiut University , Egypt

Email

effattoni@gmail.com

City

Assiut

Orcid

-

First Name

Kerolos

Last Name

Helmy

MiddleName

Nabil

Affiliation

Teaching assistant of Neuropsychiatry faculty of medicine Aswan university

Email

krollos630@gmail.com

City

Esna

Orcid

-

First Name

Ahmed

Last Name

Mohammed

MiddleName

Shoyb

Affiliation

Lecturer of Neuropsychiatry, Department of Neuropsychiatry, Faculty of Medicine, Aswan University, Egypt

Email

ahmed.shoyb@yahoo.com

City

Aswan

Orcid

-

Volume

3

Article Issue

2

Related Issue

44966

Issue Date

2023-12-01

Receive Date

2023-10-19

Publish Date

2023-12-01

Page Start

215

Page End

228

Print ISSN

2735-3109

Online ISSN

2735-3117

Link

https://aumj.journals.ekb.eg/article_332134.html

Detail API

https://aumj.journals.ekb.eg/service?article_code=332134

Order

332,134

Type

Systematic review or meta-analysis

Type Code

2,281

Publication Type

Journal

Publication Title

Aswan University Medical Journal

Publication Link

https://aumj.journals.ekb.eg/

MainTitle

Parkinson's disease and thyroid dysfunction: Effects on severity and risk of cognitive impairment Abeer A.Tony1, Emad F Kholef,2 Effat AE.Tony3, Kerollos N Helmy4, Ahmed Shoeb5

Details

Type

Article

Created At

29 Dec 2024