Background: Leadership style is the manner by which leaders influence the group members to achieve organizational goals. In nursing leadership, the effectiveness of first -line nurse manager is defined as a process whereby nurse manager influences a nursing staff to achieve a common goal. Each leadership style can have different outcomes in the nursing staff effectiveness, satisfaction and hence, make extra efforts (Albagawi, 2019). The outcomes of leadership styles were significantly related to nurses' work readiness indicating their positive effect on nurses' work readiness (Lau et al., 2020). The work readiness, has been defined as “The extent to which graduates are perceived to possess the attitudes and attributes that make them prepared or ready for success in the work environment" (Magagula et al., 2020) Objective: To identify the relationship between first -line nurse managers' leadership style outcomes and nurses' readiness to work. Settings: The study was carried out in medical, surgical inpatient care units and critical care units at Alexandria Main University hospital in Alexandria governorate. Subjects: All nursing staff (n=480), was working during the time of data collection in the previously mentioned units. Tools: Two tools were used for data collection. Tool (I) was "The Multifactor Leadership Questionnaire" in addition, nurses' demographic data. Tool (II) was the work readiness scale (WRS) tool. Results: The findings of the present study showed that there was moderate, positive and statistically significant correlation between the overall leadership style outcomes and transformational style. There was low but positive and significant correlation between the overall leadership styles outcomes and transactional style. However, there was a negative, weak and statistically significant correlations between nurses` leadership outcomes and the laissez faire style. There was a weak, positive and significant correlation between the overall FLNM leadership styles outcomes and the work readiness. But there were weak, negative and significant correlations between the laissez-faire leadership style, and work readiness. Conclusion: there was a significant relation between the outcomes of leadership style with nurses' work readiness which indicating the positive effect of the outcomes on work readiness Recommendations: Developing the professional competencies of the first- line nurse managers' leadership style through leadership training program and its impact on developing their planning skills, competencies and awareness; to achieve high quality of patient care.