Context: Patients with a tracheostomy are considered to be high risk for some complications and have numerous complexities for nurses to consider. Aim: To evaluate how tracheostomy care bundle can affect nurses' performance and patient' health outcomes. Methods: The study employed a quasi-experimental research design. The study was conducted in Benha University Hospital at intensive care unit on a convenience sample of 70 nurses and 36 tracheostomy patients using three tools: Self-administered questionnaire, St Mary's Tracheostomy Care Bundle Observational Checklist and Patient' Health Outcomes sheet. Results: Showed that total knowledge score of studied nurses was poor at pretest phase 71.4%. While being improved into good at immediate posttest 95.7% and follow up phase 87.1%.  In addition, total practice score of studied nurses was inadequate at pretest phase 81.4%. while it changed to be adequate at immediate posttest 78.6% and at follow up phase 70%. On the same line, more than half of tracheostomy patients experienced low clinical risk and complications after care bundle implemention with high statistically significant differences between pre and post bundle implementation observed as p <0.001. Conclusion: The application of tracheostomy care bundle program for nurses was successful in enhancing patients' outcomes.  Recommendation: Developing Tracheostomy care bundle booklet or poster should be involved at critical units with optimizing level of nursing training sessions to improve patient' health outcomes and quality of care provided.