A pot experiment was carried out in two successive years in early summer seasons of 2020 and 2021, under protected conditions (theram house), at the Agricultural Experimental Farm, Faculty of Agriculture Menoufia University Shebin El-Kom, Egypt. This experiment was conducted to study the effect of two sources of fertilization i.e. organic (compost “COM" and humic acid “HA") and biological (arbuscular mycorrhizal “AM" and plant growth promoting rhizobacteria “PGPR") on mitigation salinity hazard on tomato plants (hybrid 186). Saline solutions were prepared by using NaCl to induce an EC of 3 and 6 dS m^-1, in addition to tap water (0.56 dS m^-1) as a control. Comparable to un-saline treatment (tap water i.e., 0.56 dS m^-1), salinity (at 3.00 and 6.00 dS m^-1) decreased tomato plant growth, i.e., root and stem length, and fresh and dry weights of plant organs estimated in plant samples taken at 50 and 60 DAT. In addition, salinity reduced: number of days to flowering of 50% of plants, fruit set (%), leaf relative water content (RWC), and N, P, K and Ca contents in both young active and old inactive leaves. Tomato yield and it`s components were also diminished by salinity. On the other hand, salinity increased specific leaf weight, osmotic pressure in leaves, water use efficiency (WUE), leaf total sugars content, leaf proline content, electrolyte leakage in leaves, non-marketable yield, and fruit contents of TSS, Vit. C, TA and fruit firmness. Also, salinity enhanced Na and Cl contents in both young and old leaves but their concentrations were higher in older leaves than in younger ones. Salinity alleviation treatments i.e., bio and organic fertilizers used in this study all mitigated salinity stress, as they increased values of all plant growth parameters, fruit set (%), N, P, K and Ca contents in both young and old leaves, total sugars contents, yield and yield components, and Vit. C content in fruits, as well as improved plant water status and water use efficiency. Also, such treatments resulted in reducing Na and Cl contents in both young and old leaves particularly in former ones, leaf proline content, and leaf electrolyte leakage. The combined or bilateral treatments i.e., AM+PGPR and COM+HA both seems to be of a synergistic effect as they effect on alleviation salinity stress was tremendous than using each component of both alone. In addition to these combined treatments AM inoculation and COM application were the most effective treatments in terms of alleviation salinity hazards on tomato plants.