Background: Performance appraisals are one of the most important aspects of management. It creates the road for the workers' advancement and growth by helping them modify their roles, tasks, or relationships to align with performance expectations and personal preferences. Job-crafting behaviors can be reinforced and encouraged through the appraisal process Aim: Explore staff nurses' perception of performance appraisal system and its relation to job crafting behaviours Design: A descriptive correlational study design was utilized. Setting: This study was conducted in the intensive care units at El Manial Teaching Hospital. Study Sample: A convenience sample of all available staff nurses (n=105) out of (160). Tools: Two tools were used for data collection two tools were used as follows: (I) Performance Appraisal System Questionnaire and (II) Job Crafting Questionnaire. Results: The findings revealed that (67.9%) of staff nurses had a high perception level of the performance appraisal system and (66%) of them had a moderate perception level of job crafting behaviours. Conclusions: There was a highly statistically significant positive correlation between staff nurses' total perception of the performance appraisal system and their job crafting behaviors. Recommendations: Healthcare settings should develop and implement a performance reward system recognizing and rewarding nurses for their job-crafting efforts, creativity, and contributions to organizational success. Hospital administrators should identify the facilitators and obstacles to nurses' job crafting across jobs and unit types and provide training workshops or seminars that teach nurses how to identify opportunities for job crafting, set meaningful goals, and develop new skills relevant to their roles. Nurse managers should make sure that nurses are aware of all aspects of the performance appraisal process, including the standards, expectations, and appraisal criteria.