The research aimed to identify the determinants of Bedouin women's practice of entrepreneurial skills. The research was conducted in North Sinai Governorate on a sample of female respondents who benefited from entrepreneurship training programs. Their number reached 223 female respondents out of a total of 732 female respondents who obtained entrepreneurship training programs organized by civil society organizations at the destrict And the city of Al-Arish, For the analysis of the data of the study, it was quantitatively processed and analyzed statistically using numerical inventory tables, percentages, Pearson's simple correlation coefficient, and the progressive upward multiple regression coefficient. The research reached the following results: There are six independent variables that together contribute to explaining the total discrepancy between the respondents in terms of the degree of their practice of entrepreneurial skills in general, namely: the size of the network of social relations, the economic status of the family, the trend towards social and technological innovations, the extent of the contribution of civil society in providing needs, the degree of belonging to society, desire in independence. Referring to the value of the coefficient of determination R², which is 0.541, it is clear that these previous six independent variables together explain about 54.1% of the variation in the degree of the respondents' practice of these skills as a whole.