Background: Deep vein thrombosis is a medical condition that can cause disability and 
a decreased quality of life. Aim: evaluate effect of educational program for nurses' 
performance and clinical outcome regarding occurrence of Deep Vein Thrombosis 
among major orthopedic surgery patients. Design Quasi- experimental design. Setting: 
conducted at Orthopedic Department of Educational International Hospital at Tanta 
University. Subjects: Purposive sample (50) nurses and (40) adult patients that were 
divided into two groups of 20 patients each of them. Tools: 4 tools were applied Tool I: 
Nurses Assessment structure questionnaire, Tool II: Observation checklist for nurses' 
practice, Tool III: Patients Assessment Sheet, Tool IV an evaluation sheet for DVT. 
Results there was significant progress in the nurses' attitude related to the prevention of 
deep vein thrombosis. and statistical improvement in clinical outcomes in study group 
rather than control group after implementing the educational program Conclusions: the 
results concluded that implementation of the nursing educational program resulted in 
improvement in Nurses' attitude and Patients' clinical outcomes Recommendations: 
Planning educational classes for orthopedic surgical patients about prevention of DVT 
following orthopedic surgery.