Background: Chronic pancreatitis is complex conditions that are requiring multi-faceted care with
a range of interventions from a variety of specialists. Aim: This study was aimed to evaluate the
effect of implementing educational guidelines on nurse's performance for patients with chronic
pancreatitis. Subjects and Method: A quasi-experimental research design was used with a
purposive sample of nurses (50) of both sexes, who directly caring for pancreatic patient in medical
department at Tanta University. Tools: Tool (I) Nurses knowledge assessment questionnaire sheet,
it was be divided into two part: part (A) sociodemographic characteristics of nurses , part (B)
nurses' knowledge questionnaire Tool (II) nurses practice observational checklist, and Tool (III)
the comprehensive pain assessment tool (full COMPAT questionnaire). Results: The results
revealed highly significant differences were observed in the mean score of nurses' knowledge, and
practice in relation to nursing management throughout periods of the study since P=<0.001.
according to the nurse total practice score throughout period of study, this result reveals that more
than half (58%) had unsatisfactory score of practice about chronic pancreatitis care in the pre-
program implementation compared with the majority (88%) of nurses had satisfactory practice
score immediately and respectively (84%) after one month of program. Also, it was observed that
the mean score increased immediately after program compared to pre-program and decreased
gradually after one month of the study. Conclusion and Recommendations: it can be concluded
that majority studied nurses had a high level of practice and good knowledge immediately and one
month after program than pre implementation of educational program