Background: The ability to deliver comfort-based therapies to enhance a patient's quality of life 
makes palliative care knowledge crucial for nursing personnel taking care of children with 
serious illnesses. Aim: Evaluate the effect of web-based pediatric palliative care educational 
sessions on the knowledge and reported practices of nurses at Assiut University Children's 
Hospital. Research Design: A Quasi-experimental research design was utilized in this research. 
Subjects: Included a purposive sampling of 91 nurses was documented in this research. Tools of 
data collection: Two tools included Nurses' knowledge towards pediatrics palliative care, 
Nurses' personal characteristics tool and Nurses' reported practice regarding pediatric palliative 
care Results: The majority of the studied nurses (91.2%) had poor knowledge while only (8.8%) 
of them had good knowledge before web-based education compared to sixty- six percent of them 
(65.9%) had good knowledge after implementation of web-based education. A statistically 
significant difference was present between the pretest and posttest scores of the nurses regarding 
the palliative care knowledge level and self‐reported palliative care practices (P value 
<0.001).Conclusion: Nurses' knowledge as well as reported practices related to pediatric 
palliative care were enhanced after the implementation of the web-based pediatric palliative care 
education. Recommendations: To educate all of the pediatric nurses in the hospital, more 
educational sessions were recommended.