: Cryopreservation of human ovarian tissue has been widely used all 
over the world to protect fertility, not only for women undergoing chemotherapy, but also for 
women who wish to delay pregnancy for a certain period in order to preserve fertility. Aim of 
the study was to find out the effect of an educational program on knowledge and attitude of 
female students' regarding oocyte cryopreservation. Research Design: quasi-experimental 
research design was used in this study. Setting: This study was conducted at faculties of art 
and education, Zagazig University, Egypt. Sample: purposive sample composed of 115 of 
postgraduate female students. Results: After implantation of an educational program 97.2% 
of study subject shows highly satisfactory score of total knowledge compared to 12.3% in preintervention phase. As well as 92.3% of study subject reported positive attitude in posttest 
compared to 25.3% in pretest. Conclusion: The educational progam was effective on increase 
knowledge and change attitude of post graduated female students regarding oocyte 
cryopreservation. Recommendation: More efforts needed by the health care system, to 
increase the youth knowledge about ways to preserve their fertility especially unmarried girls