Background: Critical care nurses must understand the importance of neuromuscular blockade 
agent (NMBA) is used. The study aimed to evaluate the efficacy of educational module 
about patients receiving neuromuscular blockade agents on nurses' performance and patient's 
clinical outcomes. Subjects and method: All (50) nurses working in Intensive Care Unit and 
30 patients under effect of treatment with (NMBA) in Anesthesia Care Unit at Tanta 
Emergency Hospital and El-Minshawy General Hospital. Three tools were used for data 
collection. Tool I: Nurse's Assessment Tool, two parts, part one: Nurse's Socio-demographic 
Assessment, part two Nurse's Knowledge Assessment. Tool II: Nurses Practice Observational 
Checklist. Tool III: Patient Undergoing Neuromuscular Blockade Agent observation 
checklist, three parts; part one: Biosocio demographic patient data, part two: lab investigation 
part three: Neuromuscular Blockade agent side effects Observational checklist for patient. 
The Results revealed that an improvement in the nurses' knowledge and practice and 
improvement of the patient clinical outcomes. The study concluded that nurse's improvement 
in their knowledge level and practices regarding safe administration of NMBAs and this 
improvement have positive effect on patient clinical outcomes. Recommended: It can be 
recommended that for prevention of NMBAs side effects as corneal ulceration six time safe 
care per day must be done, for hypotension and tachycardia measure blood pressure, pulse 
every one hour, for bed sores change position every one hour, for edematous limbs elevation 
of lower limbs 30c.as well as applying the educational module for nurses in continuing up to 
date education.