Background: Future foresight tools used by futurists use to expand knowledge and to explore many plausible futures. Innovation is a process by which a domain, a process, or a service is renewed and brought by applying new processes. Aim: Assess nurse managers' perception about future foresight tools and innovation skills. Design: A descriptive correlational study design. Setting: at Assiut city Hospitals of the Ministry of Health and Assiut University Hospitals. Subjects: All nurse managers at Assiut city Hospitals (N. =170), and All nurse managers at Assiut University Hospitals (N. =217). Data collection Tools: Tool (I) include two parts: Part I: (personal & job characteristics for nurse managers). Part II: Future foresight questionnaire. Tool II: Innovation skills questionnaire. Results: There was a positive correlation and statistically significant difference between the perception of nurse managers for the future foresight tools and innovative skills. Conclusion: The perception of nurse managers about future foresight tools impact on the level of innovation skills which demonstrate a moderate level of perception at Assiut University Hospitals and low level of perception at Ministry of Health Hospitals. Recommendation: Holding an educational program for nurse managers in Assiut city Hospitals of the Ministry of Health to increase and develop their perception about future foresight and innovation skills.