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319284

Role of Integrons 1 and 2 in Proteus spp. and Evaluation of Some Antibiotic's Resistance Genes

Article

Last updated: 03 Jan 2025

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Abstract

A total number of 150,86 samples (57.3%) of samples were females, and 64 (42.7%) of samples were males, so from total specimens of 150 showed significant bacterial growth. The most common pathogen was proteus spp (50%), Staphylococcus spp (8.3%) Klebsiella pneumoniae (11.7 %), streptococcus spp (16.7%), Serratia marcescens (13,3%), Antibacterial susceptibility test was conducted for 30 proteus spp isolates against 20 commonly used antibacterial agents by using the disk diffusion method, the highest rate of resistance was seen with Ampicillin 30/30(100%) followed Amoxicillin- clavulanic Acid 29/30 (97.5%) and colistin 27/30 (90 %) and the low rate resistance was seen with Meropenem 0/30 (0%) and imipenem was 1/30 (7.5%), the results showed presence of integron-1 in Proteus spp isolates, from the 30 (100%) isolates of  Proteus spp was 5 (16.65 %) is positive and integron-2 was ( 83.25 %) 25 positive for 30 proteus spp isolates. The results showed that the (blaOXA-1) gene was detected in Proteus spp isolates, from the 30 (100%) isolates 9 (30.3 %) were positive. where have blaTEM gene, the result was (40%) positive, and bla SHV gene was found in 2 isolates (6.66%), and finally the bla AMP-c gene was positive in 6 isolates (19%).

DOI

10.21608/eajbsc.2023.319284

Keywords

Proteus spp, integron antibiotic resistance gene, β-lactamase

Authors

First Name

Mustafa

Last Name

AL-Fatlawi

MiddleName

R. M.

Affiliation

Al-Furat Al-Awsat Technical University, College of Health and Medical Techniques, Kufa, Iraq

Email

mustafa2alfheed22@gmail.com

City

Iraq

Orcid

-

First Name

Oday

Last Name

Zwain

MiddleName

M. H.

Affiliation

Al-Furat Al-Awsat Technical University, College of Health and Medical Techniques, Kufa, Iraq

Email

odayzwain@gmail.com

City

Iraq

Orcid

-

First Name

Zahraa

Last Name

Alquraishi

MiddleName

H.O.

Affiliation

Al-Furat Al-Awsat Technical University, College of Health and Medical Techniques, Kufa, Iraq

Email

-

City

Iraq

Orcid

-

Volume

15

Article Issue

2

Related Issue

42345

Issue Date

2023-12-01

Receive Date

2023-08-21

Publish Date

2023-10-05

Page Start

367

Page End

377

Print ISSN

2090-0767

Online ISSN

2090-083X

Link

https://eajbsc.journals.ekb.eg/article_319284.html

Detail API

https://eajbsc.journals.ekb.eg/service?article_code=319284

Order

319,284

Type

Original Article

Type Code

673

Publication Type

Journal

Publication Title

Egyptian Academic Journal of Biological Sciences. C, Physiology and Molecular Biology

Publication Link

https://eajbsc.journals.ekb.eg/

MainTitle

Role of Integrons 1 and 2 in Proteus spp. and Evaluation of Some Antibiotic's Resistance Genes

Details

Type

Article

Created At

24 Dec 2024