Background: With the growing complexity of health care, the ability to communicate becomes essential within the health team members.  Nurses interns' may lacked experiences with important communication skills and are fearful of making mistakes which may affect patient safety. One way to improve handoff communication skill among nurses interns' is through education. Aim: This study aimed to assess the effect of nursing handoff educational bundle on nurse interns' knowledge and communication competence. Research design: A quasi experimental one group pre- posttest design used to conduct this study. Setting: The study was conducted at Kafr  El-Sheikh University Hospital .Subjects: Included(95)nurse interns" enrolled in internship training year. Tools: the data for this study were collected through two tools, namely  handoff knowledge questionnaire and handoff communication competence observational checklist. Results : About one third (30.5%)  of nurse interns had satisfactory knowledge regarding  nursing handoff  before the intervention .This increased to (91.6%)  post intervention and slightly declined to (87.4%) in  follow up phase. There were a highly statistically significant improvement in all handoff communication competence dimensions in post and follow up phases (P < 0.001) as compared to pre intervention phase. Conclusion: The implementation of nursing handoff educational bundle was effective in improving nurse intern's handoff knowledge and communication competence. Recommendation: Nurse interns' handoff knowledge should be periodically refreshed through workshops and seminars in their training settings .