Background: Cervical cancer is a serious public health problem and one of the second leading causes of cancer-related mortality among women worldwide. Aim: This study aimed to evaluate Women's Perception regarding Cervical Cancer Screening Research Design: A Descriptive design was used in this study. Subjects: A purposive sample was utilized and take 382 women in three months., Setting: This study was conducted at outpatient gynecology and family planning clinics, in Elsanta central hospital in AL Gharbia governorate. Tools of date collection: 2 Tools: Tool I A structured interviewing questionnaire sheet include 3 parts the socio -demographic characteristics, Obstetrical, gynecological, and medical history and women's knowledge regarding cervical cancer screening Tool II Women 's attitude toward Cervical cancer screening measured on 3-point Likert scale. Results: This study showed that 85.6% of the studied women have poor level of knowledge regarding cervical cancer screening, 9.9% of them have fair level, 4.5% of them have good level. While 69.6% of the studied women have positive attitude toward cervical cancer screening and30.4% of them have negative attitude. Conclusion: the current study concluded that Most of the studied women had poor level of total knowledge, minority of them had fair and good level, more than two thirds of the studied women had positive attitude towards cervical cancer screening, less than one third of them had negative attitude. and there was highly significant positive correlation between total knowledge of the studied women and their total attitude. Recommendation: Design and implement of educational program to empower women's knowledge about cervical cancer screening.