Background: Pediatric liver disorders are particularly important since several childhood illnesses are risk factors for adult chronic liver diseases such as cirrhosis and hepatocellular carcinoma. Aim: The study aimed to evaluate the effect of social-platform-based education on nurses' performance regarding the care of children undergoing liver surgeries. Research design: A quasi-experimental design was utilized to achieve the aim of this study. Setting: The study was conducted at the Pediatric Surgery Unit affiliated with Sohag University hospitals. Sample: A convenient sample of 50 nurses, from the previously mentioned setting during the period of six months. Tools: two tools were used to collect data: Tool I: A structured interviewing questionnaire, and Tool II: Standardized observational checklists. Results: This study revealed that there was a statistically significant improvement in nurses' knowledge and practices post-social-platform-based education. There were statistically significant differences between nurses' knowledge and practices regarding the care of children undergoing liver surgeries and their socio-demographic characteristics. There was a positive correlation between nurses' knowledge and practices regarding the care of children undergoing liver surgeries pre- and post-social-platform-based education. Conclusion: The current study concluded that social-platform-based education has a positive effect on improving nurses' performance regarding care of children undergoing liver surgeries. Recommendation: Provide continuous in-service training programs regarding liver surgeries for nurses in different healthcare settings to improve and update their performance.