Background: A multifaceted idea, sustainability awareness includes information, attitudes, and actions about environmental, social, and economic issues. So, the current study aimed to explore the effect of social media-based educational guidelines on academic nursing students' performance regarding sustainability development. Design: Quasi-experimental research design one group pre & post-test was utilized. Setting: The study was conducted in the Faculty of Nursing, Port Said University in Egypt using an online questionnaire via Google Form and submitting the following link (https://docs.google.com/forms/dle/1FALP HKsd). Subjects: A purposive sample of academic nursing students was obtained from social media such as Facebook and WhatsApp groups who already use social media, and agreed to participate in this study, and all of them took the pre-and post-test. Tools: The Sustainability Consciousness Questionnaire (SCQ) was introduced to academic nursing students through interventions by Whats App and Facebook groups. SCQ included three parts used to measure academic nursing students' knowledge, attitudes, and behaviors regarding sustainability development. Results: After the study group was given social media-based training guidelines, the study's mean score for nursing students' knowledge, attitude, and behavior toward sustainable development increased. A highly significant difference (p≤0.05) was seen between the pre and post-social media-based educational guidance intervention. Conclusion: The study's conclusions support the idea that social media-based instructional guidelines can help nursing students perform better in terms of sustainability development. Recommendation: The concept of sustainability development ought to be incorporated into nursing courses, according to the findings. To instill a culture of sustainability development among students, nursing educators should also broaden and update their knowledge on the subject.