Background: Hearing impairment is the most common sensory defect in humans. Nurses have a primary role in communicating with and offering care to patients with hearing impairment. Aim: To evaluate the effect of educational program on nurses' performance and communication regarding patients with hearing impairment. Design: A quasi-experimental design. Sample & Methods: The study was conducted in ear, nose and throat (ENT) department at Beni-Suef University hospital. A convenient sample of 30 nurses: 12 nurses in medical ENT department, and 18 nurses in surgical ENT department in the previously mentioned setting. Tools: Four tools were used for data collection, Tool (I): A self-administered questionnaire. Tool II: Observational checklist for nurses practice regarding hearing impairment patients. Tool III: Nurses' Attitudes towards hearing impairment patients. Tool IV: Nurses' Communication with patients with hearing impairment. Results: There was a statistically significant difference between nurses' performance and communication regarding patients with hearing impairment pre- and post-application of the educational program with P= (<0.001). Conclusion: The study proved that; educational program improve nurses' performance and communication regarding patients with hearing impairment. Recommendation: Plan and implement an educational program related to nurses' performance and communication as an in-service training program for nurses as well as to be involved in nursing curriculums.