Background: Identifying adolescent awareness regarding climate change, is essential preliminary step in determining gaps and paving the way for awareness campaigns that address climate change causes and counteraction mitigation measures. Aim: This study aim to determine the effect of mobile intervention to enhance adolescents' awareness about climate change and its adverse effect. Design: A quasi-experimental research design was used for this study. Setting: This study was carried in Three secondary schools namely Fatima AlZahra, Hoda Shaarawy and 25 January official languages. affiliated to El-Massara Administration, Helwan, Cairo Governorate, Egypt.  Sample: A multi-stage random sample was used. The total number of adolescents was 377. Tools: Four tools were used in this study: First: Structured interview questionnaire which consisted of the following parts: Part 1: Characteristics data of studied adolescents, Part 2: Knowledge of studied adolescents about climate change. Second: Studied adolescents' daily life reported practice. Third: Studied adolescents' attitude Likert scale toward climate change. Fourth: Studied adolescents' awareness. Results: The current study revealed that, 54.4% and 62.3% of studied adolescents had poor knowledge and inadequate reported practices about climate change respectively at pre-intervention, which improved 80.4% and 76.1% at post-intervention respectively had good knowledge and adequate reported practices. 69.5%  of them had a negative attitude and 59.4%  of them had low awareness about climate change at  pre-intervention, which improved to 78.8% and 75.3% at post-intervention had a positive attitude and high awareness respectively toward climate change. The differences between pre and post-interventions revealed highly statistically significant differences. Conclusion: Mobile intervention had been positive effect in achieving significant improvements in adolescents' knowledge, reported practices, attitudes, and awareness regarding climate change and its adverse effect. Also, there was a positive correlation between their total knowledge, reported practices, attitudes and awareness. Recommendation: Educational programs should be designed to increase climate literacy and awareness, as well as to empower adolescents to move towards sustainability and Its adverse effect.