The present study used the assessment models to evaluate the fishery status of Neoniphon sammara in Hurghada fishing area, Red Sea, Egypt. The critical lengths of N. samara were estimated at 17.1, 14 and 15.7cm for length at first capture (L_c), length at recruitment(L_r) and length at first sexual maturity respectively with corresponding ages 2.99, 2.0 and 2.50 year respectively. Estimated L_m in relation to estimated L_c revealed that there is no risk on the sammara squirrel fish stock in Hurghada fishing area. Yield per recruit analysis with different values of T_c and M showed thatY/R and B/R are more affected by natural mortality than age at first capture. Relative yield per recruit analysis revealed that N. sammara in Hurghada, Red Sea Egypt is overexploited where the current exploitation rate (E= 0.57) is much higher than E_0.5= 0.39. Target (F_opt ) and limit (F_limit ) biological reference points (BRP) compared to current F revealing  that  N. sammara  in  Hurghada, Red Sea  are overexploited. To protect the fish stocks of N. sammara in Hurghada, Red Sea, the fishing effort should be reduced by reduction of fishing vessels and/or reduction of fishing hours.