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364545

Laparoscopic versus open total mesorectal excision in rectal cancers: a randomized-controlled trial

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Last updated: 29 Dec 2024

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Abstract

Background
Laparoscopic total mesorectal excision (lap TME) is a widely used approach for rectal cancers, but sometimes, it faces some challenges especially in obese patients with low rectal tumors and after chemoradiation. Some trials proved noninferiority of lap TME, whereas others failed, and much debate exists.
Purpose
This study was designed to compare the pathologic outcomes of laparoscopic and open TME regarding distal resection margin and circumferential resection margin. It also aimed to compare the operative and recovery data, in addition to the intraoperative and postoperative complication.
Patients and methods
We prospectively reviewed the medical records of 120 patients who underwent TME between February 2017 and February 2019. Cases were selected randomly using a closed envelope for the first admitted 120 patients. Patients were divided into two groups: laparoscopic and open groups.
Results
Each group had 60 patients with similar characteristics. Both groups revealed similar pathologic outcomes; circumferential resection margin was involved three (5.0%) in laparoscopic TME group versus five (8.33%) in open TME, with value of 0.464. TME quality was complete or near complete in 57 (95.0%) in laparoscopic group versus 54 (90.0%) in open group, with value of 0.298. Our trial revealed that laparoscopic TME had earlier recovery and shorter hospital stay compared with the open approach. Overall complications were similar: 19 (31.67%) in laparoscopic TME versus 25 (41.67%) in open TME (=0.256); however, the blood loss and wound infection were higher in the open group.
Conclusion
Laparoscopic TME improves postoperative recovery, achieves similar morbidity rates, and seemingly does not jeopardize the short-term oncological parameters compared with open surgery. However, further trials are still required.

DOI

10.4103/ejs.ejs_153_19

Keywords

circumferential resection margin, Minimally invasive surgery, Rectal Cancer, Total Mesorectal Excision

Authors

First Name

Mohamed Kamal

Last Name

Alhanafy

MiddleName

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Affiliation

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City

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Orcid

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First Name

Moharram

Last Name

Abdelsamie

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Mohammed Nazeeh Shaker

Last Name

Nassar

MiddleName

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Affiliation

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Email

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City

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Orcid

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First Name

Ahmed F.

Last Name

Elkased

MiddleName

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Affiliation

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Email

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City

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Orcid

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Volume

39

Article Issue

1

Related Issue

48958

Issue Date

2020-02-01

Receive Date

2019-08-15

Publish Date

2020-02-14

Print ISSN

1110-1121

Online ISSN

1687-7624

Link

https://ejsur.journals.ekb.eg/article_364545.html

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https://ejsur.journals.ekb.eg/service?article_code=364545

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364,545

Publication Type

Journal

Publication Title

The Egyptian Journal of Surgery

Publication Link

https://ejsur.journals.ekb.eg/

MainTitle

Laparoscopic versus open total mesorectal excision in rectal cancers: a randomized-controlled trial

Details

Type

Article

Created At

21 Dec 2024