Background: Patient rights may be considered as one of the main bases for defining the standards of clinical services. On the other hand, the concept of patient rights has been on the rise alongside the ever-growing interest of international organizations in human rights. Also nurses have more responsibility than physicians in this regard, because they are usually in closer contact with patients than other health care workers. Thus, nurses are the most suitable supporters of their rights. Aim: The aim of the study was to assess nurses' compliance toward patients' rights and its relation to patients' satisfaction. Research Design: The study was conducted using descriptive comparative research design. Setting: The study was carried out Coronary Care Unit (CCU) at Minia General Hospital and Minia University Hospital in Minia city. Subject: participated ofthe study included a convenience of patients total number (n=110) patient admitted to hospitals, and all staff nurses who working in CCU during the period of data collection. Their total numbers were (55) nurses. Tool: Two tools were used; Nurses' compliance to the patient's rights questionnaire and patient satisfaction scale. Results: there was more than half at Minia University Hospital staff nurses had high level of compliance toward  patients' rights  as  (51.9%), less than half of the sample had moderate level of compliance toward  patients' rights  as  (48.1%), also none of them were low level of compliance toward  patients' rights  in the three times observation. But nurses in General Hospital had low level of compliance toward patients' rights in the first, second, and third observation as (25.9%, 55.6% and 59.3%) respectively,  also more than one third to less than two thirds of them had moderate level of compliance toward  patients' rights in the first, second, and third observation  as  (63%, 44.4% and 37%) respectively, but the lowest percent of them have high level of compliance toward  patients' rights  in in the first, second, and third observation as (11.1%, 0.0% and 3.7%) respectively. Also more than half (50.9%) of patient at Minia University Hospital exhibit the responses toward moderate level and low half (43.6%) of them responses toward high level of satisfaction. But the majority (87.3%) of patient at Minia general hospital exhibit the responses toward moderate level and (12.7%) of them responses toward low level ofsatisfaction. Conclusions: More than half of staff nurses had high level of compliance toward patients' rights and low half (43.6%) of patients responded toward high level of satisfaction at Minia University Hospital. But about half of staff nurses on second and third observation had low level of compliance toward patients' rights and the majority of patient exhibited the responses toward moderate level of satisfaction at General University Hospital. Recommendation: Nurse need to attend training program about patient rights that enhance patient satisfaction, also the hospital should made policy, rules and regulations that enhance patient rights