Back ground: Children face several cognitive, behavioral and psychological effects that are the result of maternal employment during their early developmental years.  Aim: Study aimed to assess the effect of mothers' work on psychological well-being of their children at Benha city.  Research Design: Adescriptive design was utilized to fulfill the aim of the study .Setting: This study was conducted at selected governmental primary schools at Banha city, Qaliubiya government. Sample:  A multistage sample included400children selected from the above mentioned settings .Tools of data collection:  Tool (1): A structured interviewing questionnaire sheet, tool (2):The Stirling Children's Wellbeing Scale. Results:  Less than half of the studied sample had low level of total psychological wellbeing and less than one third had moderate level while one fifth of them have high level of total psychological wellbeing .Conclusion: Mothers' work had a negative effect on the psychological wellbeing of their children. Recommendations: Developing awareness programs for enhancing woman's knowledge for improving psychological well-being of their children.